The pair, who will clash in the run on August 26 in Las Vegas, held an international press tour to promote the fight last month in which they engaged in a number of high-profile arguments.
Both have been filmed in open workouts as well and McGregor will today fulfil the next stage of his media commitments in a conference call with outlets on both sides of the Atlantic.
Journalists will be firing questions at the double UFC champion and fans will also be able to tune into the action as it will be streamed on live on Youtube.
McGregor is due on the line at 10pm UK time and will no doubt face queries on the size of the boxing gloves set to be used, a decision on which is due today, and his controversial sparring sessions with Paulie Malignaggi.
The Irishman’s media sessions will be followed by a similar call with Mayweather on Thursday which will get underway at 11pm UK time.
He will be also be joined by Leonard Ellerbe, CEO of Mayweather Promotions.